Aph(3′)-IIc, an Aminoglycoside Resistance Determinant from Stenotrophomonas maltophilia
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چکیده
منابع مشابه
Temperature-dependent aminoglycoside resistance in Stenotrophomonas (Xanthomonas) maltophilia; alterations in protein and lipopolysaccharide with growth temperature.
Clinical strains of Stenotrophomonas (Xanthomonas) maltophilia often show large, growth temperature-dependent, variations in their susceptibility (TDVS) to aminoglycoside antibiotics. Strains showing more than a fourfold increase in susceptibility between 30 degrees and 37 degrees C (TDVS+ strains; n = 23) were contrasted with those showing lesser variation (TDVS- strains; n = 15) in studies of...
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Introduction: Stenotrophomonas maltophilia is intrinsically resistant to many antimicrobials. Like Pseudomonas spp., this bacterium has a remarkable ability to cause infections, particularly in the respiratory and urinary tracts. This study aims to determine the antimicrobial resistance pattern of S. maltophilia isolates collected from a tertiary care setting and frequency of multi, extensively...
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A cryptic multidrug resistance (MDR) system in Stenotrophomonas maltophilia, the expression of which is selectable by tetracycline, is described. Tetracycline resistance was the consequence of active efflux of the antibiotic, and it was associated with resistance to quinolones and chloramphenicol, but not to aminoglycosides or beta-lactam antibiotics. MDR is linked to the expression of an outer...
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To the Editor: Stenotrophomonas maltophilia has emerged as an important nosocomial pathogen, especially in debilitated and immunocompro-mised persons (1). However, comparatively little is known of the epidemiology of this bacterium, and sources and routes of transmission of S. mal-tophilia are not well understood. The bacterium is widely distributed in the environment, including in plant rhi-zo...
متن کاملStenotrophomonas maltophilia: an emerging global opportunistic pathogen.
Stenotrophomonas maltophilia is an emerging multidrug-resistant global opportunistic pathogen. The increasing incidence of nosocomial and community-acquired S. maltophilia infections is of particular concern for immunocompromised individuals, as this bacterial pathogen is associated with a significant fatality/case ratio. S. maltophilia is an environmental bacterium found in aqueous habitats, i...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2007
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.00795-06